August 1, 2006Journal of Clinical MicrobiologyOpen Access

Molecular Dipstick Test for Diagnosis of Sleeping Sickness

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Why the study?

Does the HAT-PCR-OC test accurately diagnose sleeping sickness in blood samples?

Population

Blood samples from 26 confirmed sleeping sickness patients, 18 negative controls, and 50 negative control…

Design

Cross-sectional

Authors

SDStijn DeborggraeveMédecins Sans Frontières FCFilip ClaesFood and Agriculture Organization of the United Nations TLThierry LaurentInstitut Pasteur

Discussion

Member takes

Implication

Supports HAT-PCR-OC accuracy in cross-sectional data; hypothesis-generating and should not yet change diagnostic practice.

Structured PICO

Does the HAT-PCR-OC test accurately diagnose sleeping sickness in blood samples?

Population

Blood samples from 26 confirmed sleeping sickness patients, 18 negative controls (nonendemic region), and 50 negative control blood samples from an endemic region (total n=94).

Intervention

HAT-PCR-OC (human African trypanosomiasis-PCR-oligochromatography) test

Outcome

Sensitivity and specificity for T. brucei detectionsurrogate

The HAT-PCR-OC test provides a rapid, highly sensitive and specific method for diagnosing sleeping sickness.

Cite This Study

Deborggraeve et al. (2006) studied this question.

synapsesocial.com/papers/6a709cbf3ce530166bc2dfc8 https://doi.org/10.1128/jcm.02594-05

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Molecular Dipstick Test for Diagnosis of Sleeping Sickness

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Molecular Dipstick Test for Diagnosis of Sleeping Sickness

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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