Development and evaluation of Morus nigra leaves transdermal patches for their anti-inflammatory activity

This study investigates the formulation and evaluation of transdermal patches incorporating Morus nigra leaves extract for their potential anti-inflammatory effects. Utilizing a solvent casting method, various formulations were developed, and their physicochemical properties, including thickness uniformity, moisture content, folding endurance, and drug content percentage, were systematically assessed. The patches exhibited satisfactory characteristics, with formulation F-3 showing superior drug content and folding endurance. The findings suggest that Morus nigra leaves extract can be effectively incorporated into transdermal patches, providing a promising alternative for the management of inflammatory conditions. Future research will focus on optimizing formulation parameters and exploring clinical applications to enhance therapeutic efficacy.