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September 1, 1964The Journal of Cell BiologyOpen Access

Sarcolemmal Invaginations Constituting the T System in Fish Muscle Fibers

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Population

Striated muscle fibers from the body and tail myotomes of a fish (black Mollie)

Comparison

Glutaraldehyde fixation vs Osmium tetroxide fixation alone

Design

Preclinical

Authors

CFClara Franzini‐ArmstrongUniversity of Maryland, BaltimoreKPKeith R. PorterUniversity of Colorado Boulder

Discussion

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Overview

Warrants no clinical change; extends ultrastructural mapping in animal muscle but leaves open cardiac translation.

Structured PICO

P
Population
Striated muscle fibers from the body and tail myotomes of a fish (black Mollie)
I
Intervention
Glutaraldehyde fixation
C
Comparator
Osmium tetroxide fixation alone
O
Outcome
Preservation of fine structure, specifically the sarcoplasmic reticulum (SR) and transverse tubular (T) systemsurrogate

Glutaraldehyde fixation improves the preservation of the T system in fish muscle fibers, revealing its continuity with the sarcolemma and supporting its role in intracellular conduction.

Cite This Study

Franzini‐Armstrong et al. (1964) studied this question.

synapsesocial.com/papers/6a709dbc75498292b70a11cdhttps://doi.org/10.1083/jcb.22.3.675
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE FINE STRUCTURE OF SHEEP MYOCARDIAL CELLS; SARCOLEMMAL INVAGINATIONS AND THE TRANSVERSE TUBULAR SYSTEM1962 · 113 citations
  2. 2THE SARCOPLASMIC RETICULUM OF STRIATED MUSCLE OF A CYCLOPOID COPEPOD1963 · 63 citations
  3. 3THE SARCOPLASMIC RETICULUM OF THE BAT CRICOTHYROID MUSCLE1962 · 254 citations
  4. 4On the time required for diffusion and its relation to processes in muscle1948 · 115 citations