October 1, 2001Anesthesia & Analgesia
Epidural Analgesia Reduces Postoperative Myocardial Infarction: A Meta-Analysis
Why the study?
Does postoperative epidural analgesia continued for more than 24 hours reduce postoperative myocardial infarction or in-hospital death in surgical patients?
Population
1173 surgical patients from 11 randomized controlled trials
Comparison
Postoperative epidural analgesia continued for… vs Nonepidural analgesia
Design
Meta-analysis
Follow-up
in-hospital
Authors
Discussion
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Member takes
Implication
Supports prolonged epidural analgesia to reduce postoperative MI in surgical patients; reinforces meta-analytic evidence without mortality benefit.
Structured PICO
Does postoperative epidural analgesia continued for more than 24 hours reduce postoperative myocardial infarction or in-hospital death in surgical patients?
P
Population
1173 surgical patients from 11 randomized controlled trials
I
Intervention
Postoperative epidural analgesia continued for more than 24 hours after surgery
C
Comparator
Nonepidural analgesia
O
Outcome
Postoperative myocardial infarction (PMI) and in-hospital deathhard clinical
Postoperative epidural analgesia, particularly thoracic epidural analgesia, continued for more than 24 hours significantly reduces the incidence of postoperative myocardial infarction.
Cite This Study
Beattie et al. (2001) studied this question.