Why the study?
Does percutaneous edge-to-edge mitral valve repair improve mitral regurgitation in a patient with mitral regurgitation?
Does percutaneous edge-to-edge mitral valve repair improve mitral regurgitation in a patient with mitral regurgitation?
This first-in-human case report demonstrates the feasibility and 2-year durability of percutaneous edge-to-edge mitral valve repair for treating mitral regurgitation.
Supports feasibility of durable percutaneous repair in one case; leaves open broader efficacy questions.
We report the first-in-human mitral valve repair using percutaneous technology that creates a "surgical-like" edge-to-edge repair. A catheter-delivered clip was introduced transseptally from the femoral vein, advanced through the mitral orifice, retracted to grasp the leaflets, and detached to create a functional double-orifice valve. The patient had an uncomplicated post-procedural course. Echocardiography at 1- and 2-years post procedure showed mild mitral regurgitation and positive ventricular remodeling. The success of this case suggests that percutaneous mitral valve repair may be a feasible therapy for certain patients suffering from mitral regurgitation.
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Condado et al. (2006) studied this question.
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