Why the study?
Does nebivolol produce nitric oxide-mediated venodilation in healthy male volunteers?
Population
11 healthy male volunteers
Comparison
Nebivolol infused into phenylephrine… vs Atenolol infusion; L-NMMA pre- and co-infusion…
Design
Other
Authors
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Nebivolol's NO-mediated venodilation may distinguish it from other beta-blockers; leaves open clinical relevance in patients.
Does nebivolol produce nitric oxide-mediated venodilation in healthy male volunteers?
Nebivolol has direct, nitric oxide-mediated venodilator effects in humans, distinguishing it from other beta-blockers like atenolol.
Bowman et al. (1994) studied this question.
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