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January 1, 1992Journal of Cardiovascular Pharmacology

Morphometric Investigation of Intramyocardial Arterioles in Right Septal Endomyocardial Biopsy of Patients with Arterial Hypertension and Left Ventricular Hypertrophy

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Population

30 patients with arterial hypertension and 10 heart donors

Design

Case-control

Authors

BSB. SchwartzkopffGTx (United States)WMW. MotzGoethe University FrankfurtSKSabine KnauerHeinrich Heine University Düsseldorf

Discussion

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Implication

Arteriolar remodeling may mark hypertensive microvascular disease independent of LVH; leaves open prognostic and therapeutic implications.

Structured PICO

P
Population
30 patients with arterial hypertension and 10 heart donors
C
Comparator
10 heart donors
O
Outcome
Morphometric characteristics of intramyocardial arterioles (external diameter, arterial wall area, perivascular fibrosis, volume density of fibrosis)surrogate

Patients with arterial hypertension exhibit thickening of intramyocardial arteriolar walls and increased fibrosis independent of left ventricular hypertrophy.

Cite This Study

Schwartzkopff et al. (1992) studied this question.

synapsesocial.com/papers/6a813d57b3060df1303bed82https://doi.org/10.1097/00005344-199206201-00004

Topics

Hypertension managementEchocardiography
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