Why the study?
Does thoracic epidural anesthesia improve cardiac function and reduce myocardial cell apoptosis in isoproterenol-induced chronic heart failure rats?
Population
Isoproterenol (ISO) induced chronic heart failure (CHF) rats
Comparison
Thoracic epidural anesthesia (TEA) for 4 weeks vs ISO-induced CHF without TEA, healthy controls…
Design
Preclinical
Follow-up
4 weeks
Authors
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Should not change practice; leaves open whether thoracic epidural anesthesia benefits heart failure patients.
Does thoracic epidural anesthesia improve cardiac function and reduce myocardial cell apoptosis in isoproterenol-induced chronic heart failure rats?
In a rat model of chronic heart failure, thoracic epidural anesthesia improved cardiac function and reduced myocardial apoptosis.
Tong et al. (2014) studied this question.
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