Population
Hypothermic heart model
Design
Preclinical
Authors
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Caution advised with pacing or epinephrine in hypothermic arrest; hypothesis-generating in animal models, human translation untested.
In hypothermic hearts, artificial acceleration decreases coronary blood flow due to extravascular compression, and epinephrine use carries a high risk of ventricular fibrillation.
Robert M. Berne (1954) studied this question.
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