3D Image-Based Computational Modeling for Patient-Specific Mechanical Analysis of Human Heart Right Ventricles.

Dalin Tang; Chun Yang; Pedro J. del Nido; Idith Haber; Tal Geva

doi:10.1038/s41598-021-88970-6

January 1, 2005METMBS

3D Image-Based Computational Modeling for Patient-Specific Mechanical Analysis of Human Heart Right Ventricles.

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Why the study?

Are plasma levels of HMGB1 associated with severity, mortality, and necroptosis markers in critically-ill patients with sepsis?

Structured PICO

Are plasma levels of HMGB1 associated with severity, mortality, and necroptosis markers in critically-ill patients with sepsis?

P

Population

265 critically-ill patients, comprising a derivation cohort of 188 prospectively enrolled patients (46 control, 58 sepsis, 84 septic shock) and a validation cohort of 77 patients with sepsis.

O

Outcome

Severity and clinical outcomes of sepsis (mortality up to 90 days), and correlation between HMGB1 and necroptosis markers (RIPK3 and MLKL).hard clinical

Implication

Plasma HMGB1 levels are significantly associated with sepsis severity, 90-day mortality, and necroptosis markers RIPK3 and MLKL.

Discussion

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Cite This Study

Tang et al. (2005) studied this question.

synapsesocial.com/papers/6a70a1bff44fa9f079de4f7e https://doi.org/10.1038/s41598-021-88970-6

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3D Image-Based Computational Modeling for Patient-Specific Mechanical Analysis of Human Heart Right Ventricles.

Structured PICO

Implication

Discussion

Cite This Study

3D Image-Based Computational Modeling for Patient-Specific Mechanical Analysis of Human Heart Right Ventricles.

Structured PICO

Implication

Discussion

Cite This Study

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