Evaluation of selective laser trabeculoplasty effectiveness in cases with pseudoexfoliation glaucoma and ocular hypertension

Purpose: The aim of the study was to evaluate and compare the effectiveness of a single-session of 180 selective laser trabeculoplasty (SLT) as primary treatment in newly diagnosed cases with pseudoexfoliation glaucoma (PEG) and ocular hypertension (OHT). Methods: Thirty-six eyes of 36 PEG cases (PEG-group) and 32 eyes of 32 OHT cases (OHT-group) were included in the study. Intraocular pressure (IOP), central corneal thickness (CCT), and endothelial cell count (ECC) were noted at baseline and post-SLT 3 rd month. IOP reduction and success rates were detected. Inter and intragroup comparisons were made Results: At baseline, age and gender distributions of groups were similar (P>0.05). Baseline IOP was 26.71.6 in PEG-group and 27.21.2 mmHg in OHT-group (P=0.648). In both groups, there was a significant decrease in IOP at 3rd month compared to baseline (P<0.001). IOP at 3 rd month was 18.91.1 in PEG-group and 19.60.6 mmHg in OHT-group (P=0.507). IOP reduction rate (29.2% vs. 27.9%, P=0.807) and success rate (69.4% vs. 75%, P=0.846) were similar in PEG-group and OHT-group. Baseline CCT was 541.425.3 in PEG-group and 543.322.1 m in OHT-group (P=0.581), while baseline ECC was 2496.5231.8 and 2512.3242.7 cells/mm 2 , respectively (P=0.324). In groups, no significant change was detected in CCT and ECC values at 3rd month compared to baseline (P>0.05). IOP, CCT, and ECC values of groups were similar at 3 rd month (P>0.05).