Why the study?
No studies had examined the relationship between hs-CRP and lipid markers, especially in dyslipidemic women.
Elevated hs-CRP correlates significantly with atherogenic lipid profiles in dyslipidemic women across menopausal stages, highlighting its potential utility for early ASCVD risk stratification.
This study found a strong association between elevated levels of highly sensitive C-reactive protein (hs-CRP) and vital lipid markers in dyslipidemic pre-, peri-,and postmenopausal women, indicating the need to screen them early for atherosclerotic cardiovascular risk. These subjects were advised to make dietary and lifestyle changes to overcome dyslipidemia and prevent the development and progression of atherosclerotic cardiovascular disease (ASCVD) during menopause. No such studies have examined the relationship between hs-CRP and lipid markers, especially in dyslipidemic women. Surprisingly, significant associations were also observed between hs-CRP and triglycerides (TG), as well as between hs-CRP and LDL-cholesterol (LDL-C) in premenopausal women with dyslipidemia. These correlations suggest that hs-CRP and the studied lipid markers are better indicators of the possible onset of ASCVD in women at later ages.
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Pavuluri et al. (2026) studied this question.
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