Twenty‐eight cases of drug‐induced aplastic anaemia have been reported to the Swedish Adverse Drug Reaction Committee during its first five years of existence. This corresponds to an incidence of 0.7 cases in 1 mill. each year but seems to represent only one third of the occurring cases. The drugs most commonly involved are oxyphenbutazone (Tanderil®), chloramphenicol and phenylbutazone (Butazolidin®) in that order. The mortality is high, 66%.
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Böttiger et al. (1972) studied this question.
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