Why the study?
Do children with familial hypercholesterolemia have altered arterial mechanical properties compared to healthy controls?
Do children with familial hypercholesterolemia have altered arterial mechanical properties compared to healthy controls?
Children with familial hypercholesterolemia exhibit increased carotid artery stiffness and endothelial dysfunction independent of blood pressure, suggesting these mechanical alterations are early markers of atheromatous changes.
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Supports early arterial stiffness and endothelial dysfunction in pediatric FH; leaves open prognostic value and need for prospective validation.
Aggoun et al. (2000) studied this question.
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