Provocative outflow test. Combining water drinking and homatropine.

We have combined instillation of guttae homatropine 2 per cent. with water drinking as a new and more powerful provocative test in a series of 24 patients suspected of open-angle glaucoma in order to compare their effect on ocular tension and facility of outflow with the effect of guttae homatropine alone and water drinking alone. The amount of water given to each patient was varied according to body weight, 20 ml./kg. being given, with the object of decreasing the variance of the observations. Spaeth (I967) used I4 ml./kg. in his water drinking tonometry test.