Why the study?
Does a loading dose of dexmedetomidine augment arterial-cardiac baroreflex function in healthy men?
Does a loading dose of dexmedetomidine augment arterial-cardiac baroreflex function in healthy men?
A loading dose of dexmedetomidine augments the arterial-cardiac baroreflex in healthy men, which may contribute to hemodynamic stabilization during rapid blood pressure changes.
Hypothesis-generating in healthy volunteers; prospective trials needed before considering baroreflex effects in clinical dexmedetomidine use.
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Takko et al. (2018) studied this question.
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