Why the study?
Comorbid depression in hypertension leads to non-adherence to antihypertensive treatment, prompting an assessment of depression magnitude, severity, and associated factors.
Approximately 37% of hypertensive patients in this Ethiopian cohort experienced depression, highlighting the need for screening and management of comorbidities and stress to improve medication adherence.
Hypothesis-generating for depression screening in hypertension care; prospective studies needed before changing practice.
Introduction Co-morbid depression in hypertension leads to non-adherence to anti-hypertensive treatment. Objective To assess the magnitude and severity of depression and associated factors among hypertensive patients attending follow-up treatment at public hospitals of Hadiya zone, Ethiopia, 2022. Methods Hospital-based cross-sectional study was conducted from January 1, to January 31, 2022. The total sample size was 315 and used a systematic random sampling technique. Data were collected through a face-to-face interview. Data were entered using Epi-data Version 4.6 and exported to SPSS Version 25 for analysis. The goodness-of-fit test was done. Binary logistic regression was done, and variables with a p-value of < .25 in the bivariable analysis were taken into the multivariable analysis. Statistically significant was declared at a p-value of < .05 with an adjusted odds ratio and 95% confidence interval. Result The magnitude of depression among hypertensive patients was 37.1% (95% CI 31.7–43.9). Regarding the severity, 56.1% had no depression, 6.7% had mild, 17.3% had moderate, 14.7% had moderately severe, and 5.1% had severe depression. Body mass index: 19.12–24.9 kg/m 2 [AOR 0.06, 95% CI: 0.02–0.23], body mass index: 25–29.9 kg/m 2 [AOR 0.08, 95% CI: 0.02–0.35], absence of family history hypertension [AOR 0.39, 95% CI: 0.18–0.85], presence of co-morbidity [AOR 2.43, 95% CI: 1.34–4.42), low perceived stress scale [AOR 0.07, 95% CI: 0.01–0.56], low medication adherence [AOR 2.70, 95% CI: 1.17–6.24], and moderate medication adherence [AOR 0.29, 95% CI: 0.09–0.88] were significantly associated. Conclusion About four in 10 hypertensive patients attending follow-up treatment were depressed. The mean score of severity of depression was mild. Body mass index, family history of hypertension, co-morbidity, perceived stress scale, and medication adherence were significantly associated with depression. Therefore, maintaining body mass index, screening and treating co-morbid illness, accommodating stress, and educating about medication adherence might minimize the risk of depression.
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Nigusu et al. (2023) studied this question.
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