Why the study?
Does cardiac sympathectomy reduce ICD shocks in a young woman with CPVT refractory to beta blockade?
Does cardiac sympathectomy reduce ICD shocks in a young woman with CPVT refractory to beta blockade?
Cardiac sympathectomy can provide durable, long-term reduction in ICD shocks for patients with CPVT who are refractory to optimal medical therapy.
Answers are grounded in this paper and cite their sources.
May support sympathectomy for refractory CPVT; hypothesis-generating and requires prospective trials.
Current recommendations for therapy of catecholaminergic ventricular tachycardia (CPVT) include beta blockade and implantable cardioverter defibrillators (ICDs). Patients may experience recurrent arrhythmias, ICD shocks and, rarely, sudden death despite optimal medical therapy. We report a young woman with CPVT who received frequent ICD shocks despite beta blockade, who subsequently underwent cardiac sympathectomy with a dramatic reduction in shocks over 10 years of follow-up.
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Makanjee et al. (2009) studied this question.
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