Why the study?
Do pharmacologic reversal agents provide safe and effective reversal of direct oral anticoagulants?
Do pharmacologic reversal agents provide safe and effective reversal of direct oral anticoagulants?
This review summarizes the efficacy and safety of emerging and historical pharmacologic reversal agents for direct oral anticoagulants, including idarucizumab and andexanet alfa.
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May improve bleeding management with DOACs; leaves open optimal protocols and comparative outcomes.
Farina et al. (2018) studied this question.