Why the study?
Does GI-262570 improve myocardial glucose oxidation and contractile function in a rat model of insulin resistance and type 2 diabetes?
Does GI-262570 improve myocardial glucose oxidation and contractile function in a rat model of insulin resistance and type 2 diabetes?
PPARgamma activation improves myocardial glucose oxidation and contractile function in a rat model of type 2 diabetes by altering the metabolic profile and reducing lipid accumulation.
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Does not support clinical use; leaves open whether PPARγ agonism improves cardiac metabolism in human diabetes.
Golfman et al. (2005) studied this question.
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