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August 2, 2006Journal of Biological ChemistryOpen Access

Constitutive GDP/GTP Exchange and Secretion-dependent GTP Hydrolysis Activity for Rab27 in Platelets

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Authors

HKHirokazu KondoTenri HospitalRSRyutaro ShirakawaTohoku UniversityTHTomohito HigashiFukushima Medical University

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Kondo et al. (2006) studied this question.

synapsesocial.com/papers/6a70ad402163a0a01bc4e519https://doi.org/10.1074/jbc.m603227200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Munc13-4 Is a GTP-Rab27-binding Protein Regulating Dense Core Granule Secretion in Platelets2004 · 223 citations
  2. 2Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.1990 · 263 citations
  3. 3A Critical Role for N-ethylmaleimide–Sensitive Fusion Protein (NSF) in Platelet Granule Secretion1999 · 55 citations
  4. 4Versatile Role of Rab27 in Membrane Trafficking: Focus on the Rab27 Effector Families2005 · 218 citations
  5. 5Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome2002 · 158 citations