Effects of different early cardiac rehabilitation exercise treatments on the prognosis of acute myocardial infarction patients receiving percutaneous coronary intervention

Huiying Liang; Xinhua Hu; Liao Hong-ying

doi:10.1016/j.clinsp.2024.100408

January 1, 2024ClinicsOpen Access

Effects of different early cardiac rehabilitation exercise treatments on the prognosis of acute myocardial infarction patients receiving percutaneous coronary intervention

View Full Paper

Ask AI

Bookmark

Share

Why the study?

Exercise rehabilitation is the core of cardiac rehabilitation and improves prognosis after PCI, but the comparative effects of different exercise-based strategies on AMI patients receiving PCI remained to be analyzed.

Do different early exercise-based cardiac rehabilitation strategies improve cardio-pulmonary function, hemodynamics, 6-minute walk distance, and quality of life compared to regular nursing in acute myocardial infarction patients receiving percutaneous coronary intervention?

Structured PICO

Do different early exercise-based cardiac rehabilitation strategies improve cardio-pulmonary function, hemodynamics, 6-minute walk distance, and quality of life compared to regular nursing in acute myocardial infarction patients receiving percutaneous coronary intervention?

P

Population

127 acute myocardial infarction (AMI) patients receiving elective percutaneous coronary intervention (PCI) (< 3 months) and complete coronary revascularization with LVEF > 45%, including 89 males and 38 females, treated at Ganzhou People's Hospital in China from January 2022 to May 2023. Key inclusion criteria: stable angina pectoris (> half an hour) with episodic post sternal dull pain and clinical symptoms, serum biomarkers of myocardial injury exceeding the upper limit of reference value at least once, and ability to conduct a treadmill rehabilitation program. Key exclusion criteria: contraindications to rehabilitation training, other disease states making it impossible to conduct the rehabilitation program, and life-threatening cardiac arrhythmias.

I

Intervention

Early exercise-based cardiac rehabilitation (CR) strategies during the recovery phase, divided into five groups: A) Continuous Resistance Exercise (COR, n=18) such as sit-ups and squats; B) Continuous Aerobic Exercise (COA, n=19) such as swimming and jogging; C) Interval Resistance Exercise (IVR, n=22) such as sit-ups and squats with intervals between COR; D) Interval Aerobic Exercise (IVA, n=21) such as HIIT; and E) Inspiratory Muscle Exercises (ITM, n=26) such as deep breathing and intercostal respiration exercises.

C

Comparator

Control group (n=21) undergoing regular nursing after PCI surgery, permitted to perform some regular exercises as they wished.

O

Outcome

Cardio-pulmonary function parameters (heart rate at anaerobic threshold, peak heart rate, oxygen uptake at anaerobic threshold, peak oxygen uptake, metabolic equivalent at anaerobic threshold, peak metabolic equivalent, maximum oxygen pulse, anaerobic threshold RER, peak RER, VE, VE/VCO2 slope, ΔVO2/ΔWR), hemodynamic parameters (LVEDD, LVEF), Six-Minute Walk Test (6MWT) distance, and quality of life (WHOQOL-BREF questionnaire) assessed at 1 month and 3 months after hospital discharge.surrogate

Early exercise-based cardiac rehabilitation—particularly interval resistance exercise—significantly improves cardiopulmonary function, LVEF, 6-minute walk distance, and quality of life compared to standard nursing in AMI patients post-PCI, although cardiopulmonary differences attenuate by three months.

Limitations

Retrospective analysis
Small sample size
Single-center study

Implication

May support tailored exercise CR post-PCI in AMI; leaves open optimal regimen for prospective trials.

Abstract

OBJECTIVES: Exercise rehabilitation is the core of Cardiac Rehabilitation (CR) and will improve the prognosis of patients receiving Percutaneous Coronary Intervention (PCI surgery). The current study retrospectively analyzed the effects of different exercise-based CR strategies on the prognosis of AMI patients receiving PCI treatment. METHODS: Clinicopathological information from 127 patients was collected and divided into different groups based on the exercise-based CR received, including Continuous Resistance Exercise (COR), Continuous Aerobic Exercise (COA), Interval Resistance Exercise (IVR), Interval Aerobic Exercise (IVA), Inspiratory Muscle Exercises (ITM), and Control. The differences regarding cardio-pulmonary function, hemodynamics, and life quality were analyzed against different CR strategies. RESULTS: All the exercise-based CR strategies showed improving effects compared with patients in the Control group regarding cardio-pulmonary parameters, with IVR showing the strongest improving effects (IVR > ITM > COR > IVA > COA) (p < 0.05) at the first recoding point. However, the improving effects of exercise-based CR declined with time. Regarding the effects on hemodynamics parameters, the improving effects of exercise-based CR were only observed regarding LVEF, and the effects of IVR were also the strongest (IVR > COR > ITM > COA > IVA) (p < 0.05). Similar improving effects were also observed for 6MWT and life quality (IVR showing the strongest improving effects) (p < 0.05), which all declined three months after the surgery. CONCLUSIONS: The current study showed that exercise-based CRs had better improving effects than the normal nursing strategy on the prognosis of AMI patients receiving PCI surgery.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Liang et al. (2024) studied this question.

synapsesocial.com/papers/6a70b112c92390ac2d07d21b https://doi.org/10.1016/j.clinsp.2024.100408

View Full Paper

Ask AI

Bookmark

Share

Effects of different early cardiac rehabilitation exercise treatments on the prognosis of acute myocardial infarction patients receiving percutaneous coronary intervention

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Effects of different early cardiac rehabilitation exercise treatments on the prognosis of acute myocardial infarction patients receiving percutaneous coronary intervention

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading