Diastolic and Systolic Heart Failure Are Distinct Phenotypes Within the Heart Failure Spectrum
Key result
Diastolic and systolic heart failure represent distinct phenotypes despite similar clinical expression.
Authors
Discussion
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Implication
Examines the characteristics of distinct heart failure phenotypes, highlighting their differences and implications for treatment.
Key Points
- To explore the distinctions between diastolic heart failure and systolic heart failure within the heart failure spectrum.
- Defined heart failure by symptoms and hemodynamic parameters.
- Identified patient populations with preserved (HFpEF) and reduced (HFrEF) ejection fraction.
- Half of the heart failure patients exhibit preserved ejection fraction (HFpEF).
- The incidence of patients with normal ejection fraction is steadily increasing.
- Resource utilization remains high in both inpatient and outpatient settings.
PICO
P
Population
Heart failure
Cite This Study
Borlaug et al. (2011) conducted an editorial in Heart failure. Diastolic and systolic heart failure represent distinct phenotypes within the heart failure spectrum, despite similarities in clinical expression.