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A Nicotiana tabacum cell line, KS-1, which is tolerant to more than 1% NaCl, was treated with buthiobate. The cells accumulated 14a-methylsterols such as obtusifoliol, instead of campesterol and sitosterol. The buthiobate-treated cells lost their salt tolerance. These results suggest that the buthiobate-induced salt sensitivity is closely associated with changes in the molecular species of sterols in the cell membranes.
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Hata et al. (1987) studied this question.
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