Construction of Tetrahydrofurans by PdII/PdIV‐Catalyzed Aminooxygenation of Alkenes

This is the authors' abstract. We don't add key points for this paper.

Resolute in the face of elimination: Substituted 3-aminotetrahydrofurans were prepared in good yield and with modest to high diastereoselectivity by the Pd-catalyzed reaction shown in the scheme (Phth=phthaloyl). Mechanistic studies indicate a PdII/PdIV catalytic cycle involving cis aminopalladation and intramolecular CO bond-forming reductive elimination with retention of configuration at the carbon atom.