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July 1, 1989The International Journal of Artificial Organs

The post: pre dialysis plasma urea nitrogen ratio to estimate K·t/V and NPCR: validation

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Why the study?

Does an empirical formula based on post/pre dialysis urea nitrogen ratio accurately estimate K.t/V and NPCR compared to standard 3-point modeling in dialysis patients?

Population

256 patients undergoing dialysis (336 three-point modeling sessions)

Comparison

Empirical formula to predict K.t/V based on the… vs Standard 3-point modeling

Design

Other

Authors

JDJohn T. DaugirdasUniversity of Illinois Chicago

Discussion

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Implication

May support simplified ratio-based K.t/V estimation in dialysis; leaves open equivalence to modeled values for clinical decisions.

Structured PICO

Does an empirical formula based on post/pre dialysis urea nitrogen ratio accurately estimate K.t/V and NPCR compared to standard 3-point modeling in dialysis patients?

P
Population
256 patients undergoing dialysis (336 three-point modeling sessions)
I
Intervention
Empirical formula to predict K.t/V based on the ratio of postdialysis to predialysis plasma urea nitrogen levels
C
Comparator
Standard 3-point modeling (variable volume single-pool model)
O
Outcome
Accuracy of predicted K.t/V and NPCR compared to modeled valuessurrogate

An empirical formula based on the post- to pre-dialysis plasma urea nitrogen ratio provides a highly accurate estimate of K.t/V compared to standard 3-point modeling.

Cite This Study

John T. Daugirdas (1989) studied this question.

synapsesocial.com/papers/6a70b96b75498292b70a2f2ahttps://doi.org/10.1177/039139888901200703
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1The post: pre-dialysis plasma urea nitrogen ratio to estimate K·t/V and NPCR: mathematical modeling1989 · 112 citations