January 10, 2012Diabetes and Vascular Disease Research

Waist circumference is a strong and independent determinant of the distribution of HDL subfractions in overweight patients with cardiovascular risk factors

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Population

117 patients with increased waist perimeter and one or more cardiovascular risk factor, not on…

Design

Cross-sectional

Authors

DRDavid RosenbaumGeneral Cardiology BHBoris HanselUniversité Claude Bernard Lyon 1 DBDominique Bonnefont‐RousselotCentre National de la Recherche Scientifique

Discussion

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Implication

Waist circumference was associated with higher HDL3c; hypothesis-generating for less protective HDL shifts in central obesity.

Structured PICO

Population

117 patients with increased waist perimeter and one or more cardiovascular risk factor, not on lipid-lowering therapy. 92 had metabolic syndrome. Mean waist circumference 102.9 cm (women) and 109.4 cm (men).

Outcome

Distribution of HDL and LDL subfractions (HDL2b, HDL2a, HDL3a, HDL3b, HDL3c and LDL1, LDL2, LDL3, LDL4)surrogate

Waist circumference is an independent predictor of a shift toward denser, potentially less protective HDL particles (HDL3c) in overweight patients with cardiovascular risk factors.

Cite This Study

Rosenbaum et al. (2012) studied this question.

synapsesocial.com/papers/6a70b9e68031ec7bb1dc88a1 https://doi.org/10.1177/1479164111431990

Topics

Women and heart disease

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Waist circumference is a strong and independent determinant of the distribution of HDL subfractions in overweight patients with cardiovascular risk factors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Waist circumference is a strong and independent determinant of the distribution of HDL subfractions in overweight patients with cardiovascular risk factors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider