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June 27, 2012Journal of the American College of CardiologyOpen Access

Current Status of Transcatheter Aortic Valve Replacement

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Population

Patients with symptomatic aortic stenosis who are not candidates for open surgery or are carefully selected…

Comparison

Transcatheter aortic valve replacement (TAVR) vs Surgical aortic valve replacement (SAVR)

Design

Review

Authors

John G. Webb
John G. WebbInterventional / Structural Cardiology
DWDavid WoodValve (United States)

Discussion

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Overview

Consolidates TAVR as standard for inoperable severe AS; leaves open durability questions for lower-risk expansion.

Structured PICO

P
Population
Patients with symptomatic aortic stenosis who are not candidates for open surgery or are carefully selected high-risk, but still operable, patients
I
Intervention
Transcatheter aortic valve replacement (TAVR)
C
Comparator
Surgical aortic valve replacement (SAVR)

TAVR is the standard of care for inoperable patients with symptomatic aortic stenosis and a viable alternative for high-risk surgical candidates, though specific procedural and durability concerns remain.

Cite This Study

Webb et al. (2012) studied this question.

synapsesocial.com/papers/6a70b9e8af0c21e939287c40https://doi.org/10.1016/j.jacc.2012.01.071

Topics

Mitral valve interventionCoronary artery disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery2010 · 7,243 citations
  2. 2Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients2011 · 6,394 citations
  3. 3Health-Related Quality of Life After Transcatheter or Surgical Aortic Valve Replacement in High-Risk Patients With Severe Aortic Stenosis2012 · 296 citations
  4. 4Health-Related Quality of Life After Transcatheter Aortic Valve Replacement in Inoperable Patients With Severe Aortic Stenosis2011 · 320 citations
  5. 5Transcatheter aortic valve implantation: early results of the FRANCE (FRench Aortic National CoreValve and Edwards) registry2010 · 558 citations