Why the study?
Does spontaneous contraction maintain the structural integrity of the contractile apparatus in primary cultures of rabbit cardiac myocytes compared to quiescent cultures?
Does spontaneous contraction maintain the structural integrity of the contractile apparatus in primary cultures of rabbit cardiac myocytes compared to quiescent cultures?
Mechanical factors such as spontaneous contraction are essential for maintaining the structural integrity of the contractile apparatus in cultured cardiac myocytes.
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Mechanical activity may preserve myocyte structure in vitro; leaves open relevance to human cardiac remodeling or therapy.
Decker et al. (1991) studied this question.
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