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September 7, 2000New England Journal of Medicine

The Role of the Interleukin-1–Receptor Antagonist in Blocking Inflammation Mediated by Interleukin-1

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Charles A. DinarelloHeart Failure & Transplant

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Charles A. Dinarello (2000) studied this question.

synapsesocial.com/papers/6a70ba785d37378ac1dddeb7 https://doi.org/10.1056/nejm200009073431011

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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Biologic basis for interleukin-1 in disease1996 · 4,381 citations
2Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice2000 · 761 citations
3Arterial Inflammation in Mice Lacking the Interleukin 1 Receptor Antagonist Gene2000 · 318 citations
4Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist1998 · 978 citations