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January 1, 1996Journal of Antimicrobial ChemotherapyOpen Access

Characterization of an inhibitor-resistant enzyme IRT-2 derived from TEM-2 β-lactamase produced by Proteus mirabilis strains

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Authors

LBLaurent BretUniversité Paris-SudCCC. ChanalCentre Hospitalier Universitaire de MontpellierDSD. SirotLaboratoire de Biotechnologie et Chimie Marines

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Bret et al. (1996) studied this question.

synapsesocial.com/papers/6a70bacd5671bbf00bc2c309https://doi.org/10.1093/jac/38.2.183
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characterization and amino acid sequence of IRT-4, a novel TEM-type enzyme with a decreased susceptibility to β-lactamase inhibitors1994 · 35 citations
  2. 2Emergence of clinical isolates of Escherichia coli producing TEM-1 derivatives or an OXA-1 beta-lactamase conferring resistance to beta-lactamase inhibitors1994 · 121 citations
  3. 3Molecular characterization of nine different types of mutants among 107 inhibitor-resistant TEM beta-lactamases from clinical isolates of Escherichia coli1995 · 112 citations
  4. 4Clinical isolates of <i>Escherichia coli</i> producing multiple TEM mutants resistant to β-lactamase inhibitors1994 · 44 citations
  5. 5Variations between the nucleotide sequences of Tn1, Tn2, and Tn3 and expression of beta-lactamase in Pseudomonas aeruginosa and Escherichia coli1987 · 81 citations