Seroprevalence and Molecular Detection of Helicobacter pylori among Patients with Dyspepsia attending Dutse General Hospital, Jigawa State - Nigeria

The impacts of Helicobacter pylori affect almost 90% of the world's population which varies substantially between nations and within populations. A total of 302 patients were included in an analytical cross-sectional study. Patients between the ages of 18 and 83 were recruited between March 2020 and March 2021, and closed-ended questionnaires were used to gather data. Five milliliters of blood were drawn from individuals with dyspepsia and centrifuged at 3000 rpm for 5 minutes. A H. pylori test kit was used to perform a serological assay for IgG antibodies. Approximately 232 individuals (76.8% greatest prevalence by age group) in this study had dyspepsia; the prevalence was 31.8% in females (96 patients) and 68.2% in males (206 patients). The findings indicated a high prevalence of H. pylori in the studied area, with a higher rate in males compared to females. Among the participants, those aged 31-40 years had the highest prevalence at 31.5%, with an average age of 35.5 years. The prevalence differs significantly based on geographic location, age, and gender. Screening of younger dyspeptic patients should be prioritized to prevent further complications, and assessing the effectiveness of diagnostic tests in younger individuals is clinically significant. Additionally, raising public awareness about the causes, transmission modes, and risk factors of H. pylori infection in the region is essential.