Why the study?
Does cognitive training improve cognitive performance in patients with mild to moderate dementia, and is this effect modulated by cognitive reserve?
Does cognitive training improve cognitive performance in patients with mild to moderate dementia, and is this effect modulated by cognitive reserve?
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Cognitive training provides greater cognitive benefits to dementia patients with lower cognitive reserve compared to those with higher cognitive reserve, suggesting cognitive reserve should be considered when predicting rehabilitation efficacy.
Cognitive reserve (CR) is a potential mechanism to cope with brain damage. The aim of this study was to evaluate the effect of CR on a cognitive training (CT) in a group of patients with dementia. Eighty six participants with mild to moderate dementia were identified by their level of CR quantified by the CR Index questionnaire (CRIq) and underwent a cycle of CT. A global measure of cognition mini mental state examination (MMSE) was obtained before (T0) and after (T1) the training. Multiple linear regression analyses highlighted CR as a significant factor able to predict changes in cognitive performance after the CT. In particular, patients with lower CR benefited from a CT program more than those with high CR. These data show that CR can modulate the outcome of a CT program and that it should be considered as a predictive factor of neuropsychological rehabilitation training efficacy in people with dementia.
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Mondini et al. (2016) studied this question.
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