Long-term outcome of epilepsy surgery in patients with tuberous sclerosis

Seizures associated with tuberous sclerosis (TS) can be difficult to control with medical therapy. The authors followed 22 patients with TS who underwent epilepsy surgery for 1 to 14 years to assess the value of epilepsy surgery and predictors of long-term postoperative outcome. Unifocal onset seizures and mild to no developmental delay at the time of surgery are predictive of excellent long-term outcome.