Why the study?
Does vagal nerve stimulation improve seizure frequency and quality of life in children with epileptic encephalopathies?
Population
16 children with epileptic encephalopathies
Comparison
Vagal nerve stimulation (VNS) vs Baseline (pre-implant)
Design
Cohort
Follow-up
at least 1 year
Authors
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VNS should not yet change practice in pediatric epileptic encephalopathies; leaves open possible subgroup benefit and requires prospective trials.
Does vagal nerve stimulation improve seizure frequency and quality of life in children with epileptic encephalopathies?
Vagal nerve stimulation in children with epileptic encephalopathies did not significantly improve overall seizure frequency or EEG, but improved perceived treatment side effects and general behavior.
Parker et al. (1999) studied this question.
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