March 1, 2017Military Medicine

Malignant Hyperthermia Susceptibility and Fitness for Duty

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Population

2 patients with prior MH-like reactions to anesthesia

Design

Case_report

Authors

MLMichael A. LeeUniversity of North Carolina at Chapel Hill EMErin B. McGlinchGene Therapy Laboratory MMMaria McGlinchMayo Clinic

Discussion

Member takes

Implication

MH crises may occur from exercise or heat alone; extends anesthetic triggers but leaves open confirmation beyond case reports.

Structured PICO

Population

2 patients with prior MH-like reactions to anesthesia (one applicant to service academies, one father of an active duty Navy chief)

Intervention

Skeletal muscle biopsy with caffeine-halothane contracture test (CHCT) and genetic analysis (RYR1 and CACNA1S sequencing)

Outcome

Diagnosis of malignant hyperthermia and determination of fitness for military service

A personal or familial history of malignant hyperthermia requires formal diagnostic testing to determine fitness for military duty, highlighting inconsistencies in current screening and medical standards.

Cite This Study

Lee et al. (2017) studied this question.

synapsesocial.com/papers/6a70c0e3f44fa9f079de730f https://doi.org/10.7205/milmed-d-16-00186

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Malignant Hyperthermia Susceptibility and Fitness for Duty

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Malignant Hyperthermia Susceptibility and Fitness for Duty

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider