This overview highlights the established safety and efficacy of oral verapamil across various cardiovascular disorders, particularly angina.
Supports ongoing verapamil use across CV disorders; confirms broad efficacy but leaves open need for modern comparative trials.
Oral verapamil approved for use in all forms of angina, with its additional heart rate-controlling properties has undergone extensive clinical investigation and use since its initial development and has been demonstrated to be safe, well-tolerated and effective over a broad range of cardiovascular disorders. Further potential therapeutic indications for verapamil use remain to be assessed. Additional research with this exciting drug is ongoing.
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Guerrero et al. (1984) studied this question.