Why the study?
Does a reversed circadian blood pressure rhythm predict fatal and nonfatal vascular events in subjects with NIDDM?
Population
288 subjects with non-insulin-dependent diabetes mellitus (NIDDM)
Comparison
Reversed circadian blood pressure rhythm (n=87) vs Normal circadian blood pressure rhythm (n=201)
Design
Cohort
Follow-up
average 4 years
Authors
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Reversed circadian BP rhythm signals higher vascular risk in NIDDM; hypothesis-generating and requires prospective validation before informing practice.
Does a reversed circadian blood pressure rhythm predict fatal and nonfatal vascular events in subjects with NIDDM?
A reversed circadian blood pressure rhythm is a significant independent predictor of fatal and nonfatal vascular events in patients with NIDDM.
Nakano et al. (1998) studied this question.
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