In anæsthetised vagotomised dogs continuous infusion of adrenaline solution depresses vasomotor activity. This depression is largely due to afferent impulses from the carotid sinus, with the chemical receptors playing a major rôle. The depression seems to be localised in the constrictor centre. It seems that a diffuse vasotatic reflex is also accentuated by the presence of adrenaline in the perfusion blood.
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Chu et al. (1938) studied this question.
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