A rare case of recurrent severe hemolytic anemia

Mild compensated hemolysis associated with mechanical heart valves is not uncommon even in the current era. Severe hemolysis is rare, usually reflects paravalvular leak. Several reports described the feasibility of transcatheter closure of paravalvular leak with devices, but their effect on hemolysis is unpredictable (Shapira et al., 2009). Here we are reporting a case of paravalvular leak with hemolytic anemia treated with multiple devices, but led to worsening of hemolytic anemia.