Mechanical force from coronary spasm may induce intraplaque hemorrhage, leading to rapid plaque progression and a layered appearance on OCT.
Hypothesis-generating for spasm-related intraplaque hemorrhage in layered plaque; single-case data leave mechanisms unresolved and should not alter practice.
area without connection to the luminal observed in this case indicates likely involvement of IPH in the progression of layered plaque, although plaque erosion and rupture are other potential underlying mechanisms and may have also occurred.It conceivable that mechanical force produced by coronary spasm may induce IPH or plaque within the pre-existing lipidic plaque, which rapidly enlarged plaque volume and led to the development of a layered feature on OCT examination.
No takes yet. Share an insight, caveat, or question.
Nishi et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: