Key result
OCT captures rapid plaque progression driven by erosion and massive thrombus in NSTE-ACS.
Why the study?
Plaque erosion is a common cause of non-ST-segment elevation myocardial infarction, but factors associated with plaque erosion and thrombosis are difficult to confirm clinically.
Case Report (n=1)
OCT is crucial for accurately diagnosing the underlying mechanism of blurred or rapidly progressing lesions identified on angiography in patients with NSTE-ACS.
Case of OCT-detected plaque erosion with massive thrombus does not alter ACS practice; leaves open confirmation of associated factors.
Acute coronary syndrome (ACS), diagnosed by optical coherence tomography (OCT), is caused primarily by plaque rupture, plaque erosion, and calcified nodules. Plaque erosion is more common in patients with non-ST-segment elevation myocardial infarction than ST-segment elevation myocardial infarction. This study reports the details of a case of ACS caused by massive thrombus formation due to plaque erosion. The factors associated with plaque erosion and thrombosis could not be confirmed on the basis of clinical examination findings and the physicians’ experience; therefore, the initial diagnosis of an ischemic event was replaced by a diagnosis of rapid plaque progression, as microscopically confirmed by OCT. Therefore, OCT examination must be performed for blurred or “rapidly progressing” lesions identified through angiography.
No takes yet. Share an insight, caveat, or question.
Li et al. (2024) conducted a case report in Non-ST-Segment Elevation Acute Coronary Syndrome (n=1). Optical coherence tomography (OCT) was evaluated on Diagnosis of rapid plaque progression. Optical coherence tomography (OCT) confirmed rapid plaque progression due to plaque erosion and massive thrombus formation in a patient with non-ST-segment elevation acute coronary syndrome.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: