Why the study?
Does nebivolol reduce blood pressure and heart rate compared to atenolol and placebo in white male subjects with essential hypertension?
Population
32 subjects
Comparison
Nebivolol 5 and 10 mg once-daily vs Atenolol 50 and 100 mg once-daily and parallel…
Design
RCT, double-blind
Follow-up
24 hours after dosing
Authors
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Supports nebivolol as alternative to atenolol for BP/HR control; confirms equivalent efficacy in this RCT.
Does nebivolol reduce blood pressure and heart rate compared to atenolol and placebo in white male subjects with essential hypertension?
Nebivolol is an effective antihypertensive beta-blocker that reduces blood pressure and heart rate to a similar extent as atenolol, but is ten times more potent on a weight-for-weight basis.
Simon et al. (1993) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: