Why the study?
Does fractionated external beam radiation inhibit neointimal hyperplasia in a rat angioplasty model?
Population
Rat angioplasty model (rodent model with unilateral balloon injury)
Comparison
External beam radiation vs Sham irradiation
Design
Preclinical, Randomly assigned
Authors
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Rat model supports fractionated radiation for restenosis prevention; leaves open clinical translation.
Does fractionated external beam radiation inhibit neointimal hyperplasia in a rat angioplasty model?
In a rat angioplasty model, fractionated external beam radiation effectively inhibits neointimal hyperplasia, suggesting a potential approach to prevent vascular restenosis.
Williams et al. (1999) studied this question.
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