Key result
Transcranial Doppler reveals elevated middle cerebral artery flow velocities linked inversely to angiographic vessel diameter.
Observational (n=38)
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The use of an ultrasonic transcranial Doppler technique for noninvasive evaluation of cerebral vasospasm is described. Middle cerebral arteries (MCA's), classified as spastic on angiography, demonstrated blood-flow velocity between 120 and 230 cm/sec. The flow velocities in these arteries had a clear inverse relationship to the diameter as measured from angiograms in 38 patients with recent subarachnoid hemorrhage. This relationship in the proximal anterior cerebral artery (ACA) was found to be more complicated to assess, due to the collateral channels in the anterior part of the circle of Willis. The authors conclude, however, that the new method of measuring vasospasm will also detect spasm in the ACA if it has a hemodynamically significant effect upon flow resistance.
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Aaslid et al. (1984) conducted an observational in Cerebral vasospasm following subarachnoid hemorrhage (n=38). Transcranial Doppler ultrasound vs. Angiography was evaluated on Middle cerebral artery blood-flow velocity and correlation with angiographic vessel diameter. Transcranial Doppler ultrasound detected blood-flow velocities of 120-230 cm/sec in spastic middle cerebral arteries, inversely relating to angiographic diameter in 38 patients.
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