Population
Nerve growth factor (NGF)-differentiated PC12 cells
Design
Preclinical
Authors
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May underlie neuroleptic effects; leaves open clinical translation and therapeutic potential in humans.
Fluspirilene inhibits neuronal N-type calcium channels, suggesting a mechanism for its neuroleptic properties and a potential target for modulating neurotransmitter release.
Grantham et al. (1994) studied this question.
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