Why the study?
Does pimozide improve clinical response compared to haloperidol in acutely hospitalized schizophrenic patients?
Population
30 acutely hospitalized schizophrenic patients
Comparison
Pimozide (40-60 mg/day) for 30 days vs Haloperidol (40-60 mg/day) for 30 days
Design
RCT, Double blind
Follow-up
30 days
Authors
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Pimozide shows no efficacy edge over haloperidol in acute schizophrenia; confirms equivalent antipsychotic effects in this RCT population.
Does pimozide improve clinical response compared to haloperidol in acutely hospitalized schizophrenic patients?
Pimozide (40-60 mg/day) has comparable antipsychotic efficacy to haloperidol in acute schizophrenia but causes more extrapyramidal side effects.
Haas et al. (1982) studied this question.
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