What question did this study set out to answer?

To evaluate the safety and efficacy of sellar reconstruction using resorbable synthetic patches, gelatin foam, and fibrin glue following transsphenoidal surgery.

November 1, 2000Journal of neurosurgery

Sellar reconstruction with resorbable vicryl patches, gelatin foam, and fibrin glue in transsphenoidal surgery: a 10-year experience with 376 patients

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Authors

RSRolf W. SeilerUniversity of Bern LMLuigi MarianiUniversity of Basel

Discussion

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Implication

Retrospective study shows low cerebrospinal fluid leak rates using resorbable patches for sellar reconstruction, indicating synthetic closure avoids autologous harvesting.

Key Points

To evaluate the safety and efficacy of sellar reconstruction using resorbable synthetic patches, gelatin foam, and fibrin glue following transsphenoidal surgery.
Reviewed 376 consecutive patients undergoing transsphenoidal surgery for pituitary adenomas, cysts, or subdiaphragmatic craniopharyngiomas over a 10-year period.
Performed sellar reconstruction using a synthetic absorbable patch made of polyglactin 910 and poly-p-dioxanone combined with gelatin foam and fibrin glue.
The overall nonendocrine postoperative morbidity rate was 2.8%, with 2 patients requiring reoperation for persistent cerebrospinal fluid leakage (0.5% overall; 0.8% in medium or large lesions).
No mortality, implant-related morbidity, or delayed empty sella syndrome occurred, and patch resorption did not hinder postoperative magnetic resonance imaging.

Cite This Study

Seiler et al. (2000) studied this question.

synapsesocial.com/papers/6a70d377febe604dd7099890 https://doi.org/10.3171/jns.2000.93.5.0762

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Implication

Retrospective study shows low cerebrospinal fluid leak rates using resorbable patches for sellar reconstruction, indicating synthetic closure avoids autologous harvesting.

Sellar reconstruction with resorbable vicryl patches, gelatin foam, and fibrin glue in transsphenoidal surgery: a 10-year experience with 376 patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Sellar reconstruction with resorbable vicryl patches, gelatin foam, and fibrin glue in transsphenoidal surgery: a 10-year experience with 376 patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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