Contemporary use of coronary artery calcium for the allocation of aspirin in light of the 2022 USPSTF guideline recommendations
Why the study?
The 2022 USPSTF guidelines lowered recommendations for aspirin in primary prevention following trials with neutral benefit and bleeding risk, creating a need to evaluate coronary artery calcium for personalizing aspirin allocation.
Does coronary artery calcium scoring help personalize the allocation of aspirin for primary prevention of cardiovascular disease?
Design
Review
Authors
Discussion
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Member takes
Implication
Limits aspirin for primary prevention to select patients; challenges prior routine use and extends USPSTF guidance with bleeding emphasis.
Structured PICO
Does coronary artery calcium scoring help personalize the allocation of aspirin for primary prevention of cardiovascular disease?
P
Population
Patients considered for primary prevention of cardiovascular disease
I
Intervention
Coronary artery calcium (CAC) scoring to guide aspirin therapy
Coronary artery calcium scoring can effectively risk-stratify patients to personalize aspirin allocation in primary prevention, balancing ASCVD benefit against bleeding risk.
Cite This Study
Verghese et al. (2022) studied this question.