Postprandial Matters: Identifying Multifactorial Determinants and Rethinking Glucose Monitoring

Postprandial glucose (PPG) is an important determinant of glycaemic control. Changes in postprandial levels may precede changes in fasting glucose levels, and postprandial hyperglycemia is an independent determinant of diabetic complications. The management of diabetes should aim to achieve overall glycaemic control, addressing both fasting and postprandial hyperglycemia. A multitude of variables, including demographics, differences in diet and lifestyle, and varied physiological factors, have been described which can alter and influence PPG levels. Therefore, inclusion of PPG in management planning is imperative. This can be done by identifying modifiable factors that positively influence PPG levels and adjusting treatment accordingly, made possible by frequent feedback and monitoring of PPG using practical approaches and individualizing the use of available technologies to achieve better overall glycaemic control.